Products Details

Natdox-LP

Natdox-LP

Natdox-LP ( doxoburicin) is an anthracycline type of chemotherapy that is used alone or with other treatments/medications to treat several different types of cancer. Natdox-LP ( doxoburicin) works by slowing or stopping the growth of cancer cells.

Mechanism of action
Natdox-LP (doxoburicin) has antimitotic and cytotoxic activity through a number of proposed mechanisms of action: Natdox-LP (doxoburicin) forms complexes with DNA by intercalation between base pairs, and it inhibits topoisomerase II activity by stabilizing the DNA-topoisomerase II complex, preventing the religation portion of the ligation-religation reaction that topoisomerase II catalyzes.